DEFINIENS EXPLORES COMPUTER-AIDED DETECTION APPLICATIONS FOR THE MEDICAL IMAGING MARKET

Released on: October 30, 2008, 8:23 am

Press Release Author: Definiens

Industry: Biotech

Press Release Summary: Advanced CAD Applications to Facilitate Faster, More Precise
Diagnostic Image Analysis

Press Release Body: Munich / Morristown, NJ - October 30, 2008 - Definiens, the
number one Enterprise Image Intelligence(tm) company, is developing computer-aided
detection (CAD) applications for the 3D and 4D medical imaging field. The
applications will help radiologists rapidly and accurately identify and track
lesions of interest, facilitating earlier detection and personalized treatments.

According to the World Health Organization, cancer is the second-leading cause of
death in the world and accounted for 7.6 million deaths worldwide in 2005.
Advancements in medical imaging systems (e.g., CT, MRI, PET) promise earlier
detection and treatment, promoting survival rates. However, prevalent use of
medical imaging has led to a dramatic increase in the volume of images to be
analyzed, resulting in higher workloads and logistical bottlenecks for clinical
radiologists.

Definiens CAD applications will support radiologists in the collection of diagnostic
data, reducing human error due to fatigue or data overload. The applications
utilize contextual information to compare images from different modalities and over
time in a consistent and reproducible manner. Definiens' applications can be
implemented in standard medical imaging systems to provide automated volumetric
measurements of almost all structures, including organs and lesions.

"Definiens aims to provide image intelligence at every stage of cancer diagnosis,
from screening to biopsy," said Frank P. Klein, VP of Medical Imaging at Definiens.
"Our software applications will assist experts in the collection of consistent and
timely information about lesions of interest, which we believe will result in more
effective patient care."

Current measurement criteria, such as RECIST for tumors, employ only one-dimensional
measurements. Definiens' CAD applications are specifically designed to measure and
track tumors volumetrically and over time, producing highly accurate assessments of
tumor size and growth. This will allow radiologists to make earlier, more informed
judgements on the efficacy of treatments and whether to continue or alter treatment
options.

"Lymph nodes play a critical role in the assessment of the spread of cancer through
the lymphatic system and the staging of almost all types of cancer and therapy
control," said Klein. "Our new applications will enable radiologists to analyze and
track lymph nodes of interest in an accurate and consistent manner. The earlier the
metastatic spread of cancer can be detected, the higher the chances are for
successful treatment."

Definiens will introduce its first medical application, Definiens LymphExpert(tm), at
RSNA 2008. The new application is designed to help radiologists analyze lymph
nodes, providing volumetric insight and time modeling functions.

Definiens in Medical Imaging
By automating image analysis, Definiens supports Healthcare providers in analyzing
and interpreting vast numbers of digital images accurately and consistently.
Definiens is working to improve the analysis of tissue samples and non-invasive
imaging, enabling translational medicine - from early diagnosis to personalized
treatment.

About Definiens
Definiens is the number one Enterprise Image IntelligenceTM company for analyzing
and interpreting images on every scale, from microscopic cell structures to
satellite images. The Definiens Cognition Network Technology(r), developed by Nobel
laureate Prof. Gerd Binnig and his team, is an advanced and robust context-based
technology designed to fulfill the image analysis requirements of the Medical, Life
Science, and Earth Science markets. The technology is modeled on the powerful human
cognitive perception processes to extract intelligence from images. Definiens
provides organizations with faster image analysis results, allowing deeper insights
enabling better business decisions. The company is headquartered in Munich, Germany
and has offices in the United States. Further information is available at
www.definiens.com.

Definiens, Definiens Cellenger, Definiens Cognition Network Technology, Definiens
eCognition, Enterprise Image Intelligence and Understanding Images are trademarks or
registered trademarks of Definiens.

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Web Site: http://www.definiens.com/news-room_138_42_0.html

Contact Details: Garry Clark
Ricochet PR
55 Broadway
New York, NY
10006

212-679-3300
gclark@ricochetpr.com

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